2022 Group Stage
Group A
| Pl | W | D | L | Diff | Pts | |||
| 1 | Palmeiras | 6 | 6 | 0 | 0 | 25:3 | 22 | 18 |
| 2 | Emelec | 6 | 2 | 2 | 2 | 14:7 | 7 | 8 |
| 3 | Dep. Tachira | 6 | 2 | 1 | 3 | 8:14 | -6 | 7 |
| 4 | Independiente Petrolero | 6 | 0 | 1 | 5 | 3:26 | -23 | 1 |
Group B
| Pl | W | D | L | Diff | Pts | |||
| 1 | Libertad Asuncion | 6 | 3 | 1 | 2 | 8:6 | 2 | 10 |
| 2 | Athletico-PR | 6 | 3 | 1 | 2 | 8:7 | 1 | 10 |
| 3 | The Strongest | 6 | 1 | 3 | 2 | 8:7 | 1 | 6 |
| 4 | Caracas | 6 | 1 | 3 | 2 | 4:8 | -4 | 6 |
Group C
| Pl | W | D | L | Diff | Pts | |||
| 1 | Estudiantes L.P | 6 | 4 | 1 | 1 | 8:5 | 3 | 13 |
| 2 | Velez Sarsfield | 6 | 2 | 2 | 2 | 12:11 | 1 | 8 |
| 3 | Nacional | 6 | 2 | 1 | 3 | 7:7 | 0 | 7 |
| 4 | Bragantino | 6 | 1 | 2 | 3 | 5:9 | -4 | 5 |
Group D
| Pl | W | D | L | Diff | Pts | |||
| 1 | Atletico-MG | 6 | 3 | 2 | 1 | 10:6 | 4 | 11 |
| 2 | Deportes Tolima | 6 | 3 | 2 | 1 | 10:9 | 1 | 11 |
| 3 | Ind. del Valle | 6 | 2 | 2 | 2 | 9:7 | 2 | 8 |
| 4 | America MG | 6 | 0 | 2 | 4 | 6:13 | -7 | 2 |
Group E
| Pl | W | D | L | Diff | Pts | |||
| 1 | Boca Juniors | 6 | 3 | 1 | 2 | 5:5 | 0 | 10 |
| 2 | Corinthians | 6 | 2 | 3 | 1 | 5:4 | 1 | 9 |
| 3 | Dep. Cali | 6 | 2 | 2 | 2 | 7:4 | 3 | 8 |
| 4 | Always Ready | 6 | 1 | 2 | 3 | 5:9 | -4 | 5 |
Group F
| Pl | W | D | L | Diff | Pts | |||
| 1 | River Plate | 6 | 5 | 1 | 0 | 18:3 | 15 | 16 |
| 2 | Fortaleza | 6 | 3 | 1 | 2 | 10:9 | 1 | 10 |
| 3 | Colo Colo | 6 | 2 | 1 | 3 | 9:13 | -4 | 7 |
| 4 | Alianza Lima | 6 | 0 | 1 | 5 | 4:16 | -12 | 1 |
Group G
| Pl | W | D | L | Diff | Pts | |||
| 1 | Colon Santa Fe | 6 | 3 | 1 | 2 | 8:8 | 0 | 10 |
| 2 | Cerro Porteno | 6 | 2 | 2 | 2 | 5:4 | 1 | 8 |
| 3 | Olimpia Asuncion | 6 | 2 | 2 | 2 | 4:4 | 0 | 8 |
| 4 | Penarol | 6 | 2 | 1 | 3 | 5:6 | -1 | 7 |
Group H
| Pl | W | D | L | Diff | Pts | |||
| 1 | Flamengo RJ | 6 | 5 | 1 | 0 | 15:6 | 9 | 16 |
| 2 | Talleres Cordoba | 6 | 3 | 2 | 1 | 6:5 | 1 | 11 |
| 3 | U. Catolica | 6 | 1 | 1 | 4 | 5:10 | -5 | 4 |
| 4 | Sporting Cristal | 6 | 0 | 2 | 4 | 3:8 | -5 | 2 |
Promotion ~ Copa Libertadores (Play Offs: 1/8~finals)
Promotion ~ Copa Sudamericana (Play Offs: 1/8~finals)
2022 Play Offs
1/8-finals
| 1 | Palmeiras (1) | Cerro Porteno (16) | 5 : 0, 3 : 0 |
| 2 | Atletico-MG (5) | Emelec (14) | 1 : 0, 1 : 1 |
| 3 | Libertad Asuncion (6) | Athletico-PR (12) | 1 : 1, 1 : 2 |
| 4 | Estudiantes L.P. (4) | Fortaleza (11) | 3 : 0, 1 : 1 |
| 5 | Flamengo RJ (3) | Deportes Tolima (9) | 7 : 1, 1 : 0 |
| 6 | Boca Juniors (8) | Corinthians (13) | 0 : 1, 0 : 0 |
| 7 | Colon Santa Fe (7) | Talleres Cordoba (10) | 0 : 2, 1 : 1 |
| 8 | River Plate (2) | Velez Sarsfield (15) | 0 : 0, 0 : 1 |
Quarter-finals
| 1 | Palmeiras (1) | Atletico-MG (5) | 1 : 0, 2 : 2 |
| 2 | Athletico-PR (12) | Estudiantes L.P. (4) | 1 : 0, 0 : 0 |
| 3 | Flamengo RJ (3) | Corinthians (13) | 1 : 0, 2 : 0 |
| 4 | Talleres Cordoba (10) | Velez Sarsfield (15) | 0 : 1, 2 : 3 |
Semi-finals
| 1 | Palmeiras (1) | Athletico-PR (12) | 2 : 2, 0 : 1 |
| 2 | Flamengo RJ (3) | Velez Sarsfield (15) | 2 : 1, 4 : 0 |
Final
| 1 | Athletico-PR (12) | Flamengo RJ (3) | 0 : 1 |
2022 Qualification
Quarter-finals
| 1 | Millonarios | Bye | |
| 2 | Bye | Fluminense | |
| 3 | Cesar Vallejo | Olimpia Asuncion | 0 : 2, 0 : 1 |
| 4 | Bye | Atl. Nacional | |
| 5 | A. Italiano | Bye | |
| 6 | Bye | Estudiantes L.P. | |
| 7 | Everton | Bye | |
| 8 | Bye | Monagas | |
| 9 | Lara | Bolivar | 0 : 4, 2 : 3 |
| 10 | Bye | U. Catolica | |
| 11 | Plaza Colonia | Bye | |
| 12 | Bye | The Strongest | |
| 13 | America MG | Bye | |
| 14 | Bye | Guarani | |
| 15 | Montevideo City | Barcelona SC | 0 : 1, 1 : 1 |
| 16 | Bye | U. de Deportes |
Semi-finals
| 1 | Millonarios | Fluminense | 0 : 2, 1 : 2 |
| 2 | Olimpia Asuncion | Atl. Nacional | 1 : 1, 3 : 1 |
| 3 | A. Italiano | Estudiantes L.P. | 0 : 2, 1 : 0 |
| 4 | Everton | Monagas | 0 : 1, 3 : 0 |
| 5 | Bolivar | U. Catolica | 0 : 2, 1 : 1 |
| 6 | Plaza Colonia | The Strongest | 0 : 3, 2 : 0 |
| 7 | America MG | Guarani | 4 : 2, 0 : 1 |
| 8 | Barcelona SC | U. de Deportes | 1 : 0, 2 : 0 |
Final
| 1 | Fluminense | Olimpia Asuncion | 0 : 3, 3 : 1 |
| 2 | Estudiantes L.P. | Everton | 1 : 0, 1 : 0 |
| 3 | U. Catolica | The Strongest | 1 : 2, 0 : 0 |
| 4 | America MG | Barcelona SC | 1 : 0, 0 : 0 |
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