2012
1/64-finals
1/32-finals
| 1 | Sporting Kansas City | Bye | |
| 2 | KC Athletics | Orlando City | 0 : 7 |
| 3 | Tampa Bay | Jacksonville United | 3 : 0 |
| 4 | Bye | Colorado Rapids | |
| 5 | Michigan Bucks | Pittsburgh | 1 : 0 |
| 6 | Bye | Chicago Fire | |
| 7 | Columbus Crew | Bye | |
| 8 | Chicago Premier | Dayton | 1 : 2 |
| 9 | Penn | Long Island | 2 : 0 |
| 10 | Bye | New England Revolution | |
| 11 | Charleston | Reading | 2 : 1 |
| 12 | Bye | New York Red Bulls | |
| 13 | DC United | Bye | |
| 14 | Aegean Hawks | Richmond Kickers | 0 : 4 |
| 15 | Rochester New York | Brooklyn Italians | 3 : 0 |
| 16 | Bye | Philadelphia Union | |
| 17 | Chivas USA | Bye | |
| 18 | Orange County SC | Ventura | 1 : 3 |
| 19 | Los Angeles Galaxy | Bye | |
| 20 | PSA Elite | North Carolina | 0 : 6 |
| 21 | San Antonio | Laredo Heat | 2 : 0 |
| 22 | Bye | Houston Dynamo | |
| 23 | FC Dallas | Bye | |
| 24 | Chivas Patriots | Charlotte Eagles | 0 : 1 |
| 25 | San Jose Earthquakes | Bye | |
| 26 | Fuego | Fort Lauderdale Strikers | 2 : 7 |
| 27 | Real Salt Lake | Bye | |
| 28 | Menace | Minnesota United | 0 : 2 |
| 29 | Cal | Wilmington Hammerheads | 4 : 0 |
| 30 | Bye | Portland Timbers | |
| 31 | Atlanta SC | Georgia Revolution | 1 : 0 |
| 32 | Bye | Seattle Sounders |
1/16-finals
| 1 | Sporting Kansas City | Orlando City | 3 : 2 |
| 2 | Tampa Bay | Colorado Rapids | 1 : 3 |
| 3 | Michigan Bucks | Chicago Fire | 3 : 2 |
| 4 | Columbus Crew | Dayton | 1 : 2 |
| 5 | Penn | New England Revolution | 4 : 3 |
| 6 | Charleston | New York Red Bulls | 0 : 3 |
| 7 | DC United | Richmond Kickers | 2 : 1 |
| 8 | Rochester New York | Philadelphia Union | 0 : 3 |
| 9 | Chivas USA | Ventura | 1 : 0 |
| 10 | Los Angeles Galaxy | North Carolina | 1 : 2 |
| 11 | San Antonio | Houston Dynamo | 1 : 0 |
| 12 | FC Dallas | Charlotte Eagles | 0 : 2 |
| 13 | San Jose Earthquakes | Fort Lauderdale Strikers | 2 : 1 |
| 14 | Real Salt Lake | Minnesota United | 1 : 3 |
| 15 | Cal | Portland Timbers | 1 : 0 |
| 16 | Atlanta SC | Seattle Sounders | 1 : 5 |
1/8-finals
Quarter-finals
| 1 | Sporting Kansas City | Dayton | 3 : 0 |
| 2 | Penn | Philadelphia Union | 2 : 5 |
| 3 | Chivas USA | Charlotte Eagles | 2 : 1 |
| 4 | San Jose Earthquakes | Seattle Sounders | 0 : 1 |
Semi-finals
| 1 | Sporting Kansas City | Philadelphia Union | 2 : 0 |
| 2 | Chivas USA | Seattle Sounders | 1 : 4 |
Final
| 1 | Sporting Kansas City | Seattle Sounders | 2 : 1 |
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