2021 Main
| Pl | W | L | Pts | |||
| 1 | Olimpia | 11 | 8 | 3 | 987:916 | 19 |
| 2 | Malvin | 11 | 7 | 4 | 881:826 | 18 |
| 3 | Nacional | 11 | 7 | 4 | 866:818 | 18 |
| 4 | Urunday | 11 | 7 | 4 | 823:779 | 18 |
| 5 | Bigua | 11 | 7 | 4 | 744:725 | 18 |
| 6 | Defensor | 11 | 6 | 5 | 840:838 | 17 |
| 7 | Penarol | 11 | 5 | 6 | 790:792 | 16 |
| 8 | Capitol | 11 | 5 | 6 | 764:790 | 16 |
| 9 | Aguada | 11 | 5 | 6 | 904:954 | 16 |
| 10 | Goes | 11 | 4 | 7 | 629:693 | 15 |
| 11 | Trouville | 11 | 3 | 8 | 822:856 | 14 |
| 12 | Hebraica y Macabi | 11 | 2 | 9 | 901:964 | 13 |
Promotion ~ Liga Uruguaya (Play Offs: Quarter~finals)
Promotion ~ Liga Uruguaya (Play Offs: 1/8~finals)
2021 Play Offs
1/8-finals
| 1 | Urunday (2) | Bye | |
| 2 | Penarol (7) | Goes (10) | 2 : 1 |
| 3 | Nacional (3) | Bye | |
| 4 | Defensor (6) | Trouville (11) | 2 : 0 |
| 5 | Olimpia (1) | Bye | |
| 6 | Aguada (8) | Capitol (9) | 1 : 2 |
| 7 | Bigua (4) | Bye | |
| 8 | Malvin (5) | Hebraica y Macabi (12) | 2 : 0 |
Quarter-finals
| 1 | Urunday (2) | Penarol (7) | 2 : 0 |
| 2 | Nacional (3) | Defensor (6) | 2 : 0 |
| 3 | Olimpia (1) | Capitol (9) | 2 : 1 |
| 4 | Bigua (4) | Malvin (5) | 2 : 0 |
Semi-finals
| 1 | Urunday (2) | Nacional (3) | 1 : 3 |
| 2 | Olimpia (1) | Bigua (4) | 0 : 3 |
Final
| 1 | Nacional (3) | Bigua (4) | 2 : 3 |
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