EN
2022
1/64-finals
| 1 | America De Cali | Bye | |
| 5 | Chico | Bye | |
| 6 | Real Santander | Barranquilla | 0 : 0, 3 : 0 |
| 8 | Bye | U. Magdalena | |
| 9 | La Equidad | Bye | |
| 13 | Bucaramanga | Bye | |
| 16 | Bye | Envigado | |
| 17 | Atl. Nacional | Bye | |
| 21 | Quindio | Bogota | 2 : 2, 1 : 0 |
| 22 | Orsomarso | Llaneros | 0 : 2, 0 : 0 |
| 24 | Bye | Once Caldas | |
| 25 | Junior | Bye | |
| 29 | Santa Fe | Bye | |
| 32 | Bye | Dep. Pasto | |
| 33 | Dep. Cali | Bye | |
| 37 | Boca Juniors | Fortaleza | 0 : 1, 0 : 1 |
| 38 | Real Soacha | Atletico F.C. | 1 : 0, 1 : 1 |
| 40 | Bye | Cortulua | |
| 41 | Millonarios | Bye | |
| 45 | Jaguares de Cordoba | Bye | |
| 48 | Bye | Petrolera | |
| 49 | Ind. Medellin | Bye | |
| 53 | Tigres | Leones | 1 : 1, 2 : 0 |
| 54 | Huila | Cartagena | 0 : 0, 1 : 0 |
| 56 | Bye | Patriotas | |
| 57 | Deportes Tolima | Bye | |
| 61 | Pereira | Bye | |
| 64 | Bye | Aguilas |
1/32-finals
| 1 | America De Cali | Bye | |
| 3 | Chico | Real Santander | 1 : 2, 0 : 1 |
| 4 | Bye | U. Magdalena | |
| 5 | La Equidad | Bye | |
| 7 | Bucaramanga | Bye | |
| 8 | Bye | Envigado | |
| 9 | Atl. Nacional | Bye | |
| 11 | Quindio | Llaneros | 0 : 2, 3 : 0 |
| 12 | Bye | Once Caldas | |
| 13 | Junior | Bye | |
| 15 | Santa Fe | Bye | |
| 16 | Bye | Dep. Pasto | |
| 17 | Dep. Cali | Bye | |
| 19 | Fortaleza | Real Soacha | 1 : 1, 2 : 0 |
| 20 | Bye | Cortulua | |
| 21 | Millonarios | Bye | |
| 23 | Jaguares de Cordoba | Bye | |
| 24 | Bye | Petrolera | |
| 25 | Ind. Medellin | Bye | |
| 27 | Tigres | Huila | 2 : 0, 2 : 0 |
| 28 | Bye | Patriotas | |
| 29 | Deportes Tolima | Bye | |
| 31 | Pereira | Bye | |
| 32 | Bye | Aguilas |
1/16-finals
| 1 | America De Cali | Bye | |
| 2 | Real Santander | U. Magdalena | 1 : 5, 1 : 3 |
| 3 | La Equidad | Bye | |
| 4 | Bucaramanga | Envigado | 3 : 0, 0 : 0 |
| 5 | Atl. Nacional | Bye | |
| 6 | Quindio | Once Caldas | 0 : 1, 0 : 0 |
| 7 | Junior | Bye | |
| 8 | Santa Fe | Dep. Pasto | 3 : 0, 1 : 0 |
| 9 | Dep. Cali | Bye | |
| 10 | Fortaleza | Cortulua | 1 : 0, 1 : 0 |
| 11 | Millonarios | Bye | |
| 12 | Jaguares de Cordoba | Petrolera | 2 : 1, 1 : 1 |
| 13 | Ind. Medellin | Bye | |
| 14 | Tigres | Patriotas | 1 : 0, 0 : 0 |
| 15 | Deportes Tolima | Bye | |
| 16 | Pereira | Aguilas | 2 : 2, 1 : 0 |
1/8-finals
| 1 | America De Cali | U. Magdalena | 1 : 2, 1 : 2 |
| 2 | La Equidad | Bucaramanga | 0 : 0, 2 : 0 |
| 3 | Atl. Nacional | Once Caldas | 2 : 1, 3 : 0 |
| 4 | Junior | Santa Fe | 1 : 0, 2 : 1 |
| 5 | Dep. Cali | Fortaleza | 1 : 1, 1 : 3 |
| 6 | Millonarios | Jaguares de Cordoba | 1 : 1, 3 : 0 |
| 7 | Ind. Medellin | Tigres | 2 : 1, 1 : 0 |
| 8 | Deportes Tolima | Pereira | 1 : 1, 3 : 2 |
Quarter-finals
| 1 | U. Magdalena | La Equidad | 2 : 1, 1 : 1 |
| 2 | Atl. Nacional | Junior | 1 : 1, 0 : 3 |
| 3 | Fortaleza | Millonarios | 2 : 3, 0 : 3 |
| 4 | Ind. Medellin | Deportes Tolima | 0 : 1, 3 : 1 |
Semi-finals
| 1 | U. Magdalena | Junior | 0 : 2, 1 : 0 |
| 2 | Millonarios | Ind. Medellin | 2 : 2, 2 : 0 |
Final
| 1 | Junior | Millonarios | 0 : 2, 1 : 0 |
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