español
2021
1/64-finals
| 1 | Chico | Bye | |
| 3 | Huila | Cartagena | 2 : 3, 1 : 2 |
| 4 | Llaneros | Atletico F.C. | 4 : 0, 0 : 0 |
| 8 | Bye | La Equidad | |
| 9 | Aguilas | Bye | |
| 16 | Bye | Deportes Tolima | |
| 17 | Pereira | Bye | |
| 19 | U. Magdalena | Boca Juniors | 1 : 1, 0 : 1 |
| 20 | Real Soacha | Orsomarso | 1 : 0, 0 : 0 |
| 24 | Bye | Junior | |
| 25 | Petrolera | Bye | |
| 28 | Bye | Millonarios | |
| 32 | Bye | Dep. Pasto | |
| 33 | Patriotas | Bye | |
| 35 | Leones | Fortaleza | 2 : 1, 0 : 0 |
| 36 | Cortulua | Real Santander | 1 : 2, 1 : 1 |
| 40 | Bye | Atl. Nacional | |
| 41 | Bucaramanga | Bye | |
| 44 | Bye | Envigado | |
| 48 | Bye | Santa Fe | |
| 49 | Jaguares de Cordoba | Bye | |
| 51 | Quindio | Barranquilla | 0 : 1, 1 : 1 |
| 52 | Bogota | Tigres | 0 : 2, 1 : 0 |
| 56 | Bye | America De Cali | |
| 57 | Ind. Medellin | Bye | |
| 60 | Bye | Once Caldas | |
| 64 | Bye | Dep. Cali |
1/32-finals
| 1 | Chico | Bye | |
| 2 | Cartagena | Llaneros | 0 : 1, 0 : 0 |
| 4 | Bye | La Equidad | |
| 5 | Aguilas | Bye | |
| 8 | Bye | Deportes Tolima | |
| 9 | Pereira | Bye | |
| 10 | Boca Juniors | Real Soacha | 4 : 1, 0 : 2 |
| 12 | Bye | Junior | |
| 13 | Petrolera | Bye | |
| 14 | Bye | Millonarios | |
| 16 | Bye | Dep. Pasto | |
| 17 | Patriotas | Bye | |
| 18 | Leones | Real Santander | 0 : 2, 1 : 3 |
| 20 | Bye | Atl. Nacional | |
| 21 | Bucaramanga | Bye | |
| 22 | Bye | Envigado | |
| 24 | Bye | Santa Fe | |
| 25 | Jaguares de Cordoba | Bye | |
| 26 | Barranquilla | Tigres | 3 : 0, 1 : 1 |
| 28 | Bye | America De Cali | |
| 29 | Ind. Medellin | Bye | |
| 30 | Bye | Once Caldas | |
| 32 | Bye | Dep. Cali |
1/16-finals
| 1 | Chico | Llaneros | 2 : 2, 1 : 2 |
| 2 | Bye | La Equidad | |
| 3 | Aguilas | Bye | |
| 4 | Bye | Deportes Tolima | |
| 5 | Pereira | Boca Juniors | 1 : 0, 1 : 0 |
| 6 | Bye | Junior | |
| 7 | Petrolera | Millonarios | 1 : 1, 1 : 0 |
| 8 | Bye | Dep. Pasto | |
| 9 | Patriotas | Real Santander | 3 : 3, 1 : 0 |
| 10 | Bye | Atl. Nacional | |
| 11 | Bucaramanga | Envigado | 2 : 1, 1 : 1 |
| 12 | Bye | Santa Fe | |
| 13 | Jaguares de Cordoba | Barranquilla | 0 : 2, 3 : 0 |
| 14 | Bye | America De Cali | |
| 15 | Ind. Medellin | Once Caldas | 3 : 1, 1 : 1 |
| 16 | Bye | Dep. Cali |
1/8-finals
| 1 | Llaneros | La Equidad | 0 : 0, 0 : 1 |
| 2 | Aguilas | Deportes Tolima | 0 : 0, 0 : 1 |
| 3 | Pereira | Junior | 2 : 0, 3 : 4 |
| 4 | Petrolera | Dep. Pasto | 2 : 3, 1 : 3 |
| 5 | Patriotas | Atl. Nacional | 1 : 2, 0 : 3 |
| 6 | Bucaramanga | Santa Fe | 0 : 1, 0 : 1 |
| 7 | Jaguares de Cordoba | America De Cali | 1 : 2, 0 : 0 |
| 8 | Ind. Medellin | Dep. Cali | 1 : 3, 2 : 2 |
Quarter-finals
| 1 | La Equidad | Deportes Tolima | 0 : 2, 0 : 0 |
| 2 | Pereira | Dep. Pasto | 3 : 1, 2 : 3 |
| 3 | Atl. Nacional | Santa Fe | 2 : 0, 1 : 2 |
| 4 | America De Cali | Dep. Cali | 0 : 1, 2 : 2 |
Semi-finals
| 1 | Deportes Tolima | Pereira | 1 : 2, 0 : 0 |
| 2 | Atl. Nacional | Dep. Cali | 1 : 0, 2 : 2 |
Final
| 1 | Pereira | Atl. Nacional | 1 : 0, 0 : 5 |
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