2021 Main
| Pl | W | D | L | Diff | Pts | |||
| 1 | Albion | 22 | 13 | 5 | 4 | 31:18 | 13 | 44 |
| 2 | Danubio | 22 | 12 | 5 | 5 | 24:14 | 10 | 41 |
| 3 | Racing Montevideo | 22 | 10 | 8 | 4 | 27:16 | 11 | 38 |
| 4 | Defensor Sp | 22 | 11 | 4 | 7 | 33:21 | 12 | 37 |
| 5 | CA Cerro | 22 | 10 | 7 | 5 | 26:20 | 6 | 37 |
| 6 | Central Esp | 22 | 9 | 6 | 7 | 29:29 | 0 | 33 |
| 7 | Juventud | 22 | 8 | 5 | 9 | 27:27 | 0 | 29 |
| 8 | Uruguay Montevideo | 22 | 7 | 4 | 11 | 21:27 | -6 | 25 |
| 9 | Atenas | 22 | 5 | 9 | 8 | 20:17 | 3 | 24 |
| 10 | Rampla Juniors | 22 | 5 | 6 | 11 | 14:32 | -18 | 21 |
| 11 | Villa Teresa | 22 | 4 | 6 | 12 | 17:32 | -15 | 18 |
| 12 | Rocha | 22 | 4 | 3 | 15 | 20:36 | -16 | 15 |
Promotion ~ Primera Division (Apertura: )
Promotion ~ Segunda Division (Play Offs: )
2021 Play Offs
Semi-finals
| 1 | CA Cerro | Defensor Sp. | 1 : 0, 1 : 2 |
| 2 | Central Esp. | Racing Montevideo | 1 : 1, 0 : 0 |
Final
| 1 | Defensor Sp. | Racing Montevideo | 0 : 0, 3 : 0 |
2021 Relegation
Final
| 1 | Villa Teresa | La Luz | 1 : 4, 2 : 0 |
Redes Sociales