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2022 Apertura
Group A
| Pl | W | D | L | Diff | Pts | |||
| 1 | Artemisa | 14 | 11 | 2 | 1 | 39:12 | 27 | 35 |
| 2 | FC La Habana | 13 | 8 | 2 | 3 | 27:13 | 14 | 26 |
| 3 | FC Cienfuegos | 14 | 7 | 4 | 3 | 28:20 | 8 | 25 |
| 4 | FC Villa Clara | 13 | 7 | 2 | 4 | 19:14 | 5 | 23 |
| 5 | Pinar del Rio | 13 | 4 | 5 | 4 | 13:14 | -1 | 17 |
| 6 | Matanzas | 12 | 3 | 2 | 7 | 12:23 | -11 | 11 |
| 7 | Mayabeque Guines | 13 | 1 | 1 | 11 | 6:32 | -26 | 4 |
| 8 | Juventud | 10 | 1 | 0 | 9 | 8:24 | -16 | 3 |
Group B
| Pl | W | D | L | Diff | Pts | |||
| 1 | FC Santiago de Cuba | 14 | 12 | 1 | 1 | 32:8 | 24 | 37 |
| 2 | FC Camaguey | 14 | 8 | 3 | 3 | 24:14 | 10 | 27 |
| 3 | Las Tunas | 13 | 8 | 2 | 3 | 19:8 | 11 | 26 |
| 4 | FC Guantanamo | 14 | 6 | 5 | 3 | 20:10 | 10 | 23 |
| 5 | CF Granma | 14 | 4 | 5 | 5 | 17:15 | 2 | 17 |
| 6 | FC Ciego de Avila | 14 | 3 | 3 | 8 | 6:21 | -15 | 12 |
| 7 | Holguin | 13 | 2 | 3 | 8 | 8:20 | -12 | 9 |
| 8 | FC Sancti Spiritus | 14 | 0 | 2 | 12 | 1:31 | -30 | 2 |
Promotion ~ Liga Nacional (Apertura ~ Play Offs: )
Promotion ~ Liga Nacional (Clausura: )
2022 Apertura - Play Offs
Final
| 1 | Artemisa | FC Santiago de Cuba | 0 : 7 |
2022 Clausura
| Pl | W | D | L | Diff | Pts | |||
| 1 | Artemisa | 14 | 11 | 0 | 3 | 27:13 | 14 | 33 |
| 2 | FC Santiago de Cuba | 14 | 10 | 2 | 2 | 31:8 | 23 | 32 |
| 3 | FC Camaguey | 14 | 9 | 1 | 4 | 22:12 | 10 | 28 |
| 4 | FC La Habana | 14 | 8 | 1 | 5 | 31:18 | 13 | 25 |
| 5 | FC Guantanamo | 14 | 4 | 3 | 7 | 18:17 | 1 | 15 |
| 6 | Las Tunas | 14 | 3 | 3 | 8 | 20:39 | -19 | 12 |
| 7 | FC Cienfuegos | 14 | 2 | 3 | 9 | 13:28 | -15 | 9 |
| 8 | FC Villa Clara | 14 | 2 | 1 | 11 | 20:47 | -27 | 7 |
Promotion ~ Liga Nacional (Grand Final: Final)
2022 Grand Final
Final
| 1 | Artemisa | FC Santiago de Cuba | 2 : 0, 0 : 1 |
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