EN
2021
1/16-finals
| 1 | Verdes | AD Santos | 1 : 5, 0 : 1 |
| 2 | Bye | Plaza Amador | |
| 3 | Forge | FAS | 2 : 2, 3 : 1 |
| 4 | Bye | Independiente | |
| 5 | Diriangen | Marathon | 1 : 2, 0 : 1 |
| 6 | Bye | Esteli | |
| 7 | Samaritaine | Deportivo Universitario (WO.) | |
| 8 | Bye | Motagua | |
| 9 | Inter Moengotapoe | Bye | |
| 10 | Bye | Olimpia | |
| 11 | Guastatoya | Bye | |
| 12 | Bye | Alajuelense | |
| 13 | Santa Lucia | Metropolitan FA | 2 : 1, 3 : 0 |
| 14 | Bye | Saprissa | |
| 15 | Comunicaciones | 11 Deportivo | 3 : 0, 1 : 1 |
| 16 | Bye | Alianza FC |
1/8-finals
| 1 | AD Santos | Plaza Amador | 2 : 0, 1 : 0 |
| 2 | Forge | Independiente | 2 : 0, 0 : 0 |
| 3 | Marathon | Esteli | 1 : 2, 2 : 0 |
| 4 | Deportivo Universitario | Motagua | 0 : 1, 2 : 2 |
| 5 | Inter Moengotapoe | Olimpia | 0 : 6 |
| 6 | Guastatoya | Alajuelense | 2 : 2, 1 : 1 |
| 7 | Santa Lucia | Saprissa | 2 : 4, 0 : 2 |
| 8 | Comunicaciones | Alianza FC | 1 : 0, 2 : 1 |
Quarter-finals
| 1 | AD Santos | Forge | 0 : 3, 3 : 1 |
| 2 | Marathon | Motagua | 0 : 2, 0 : 2 |
| 3 | TBD #5 | Guastatoya | |
| 4 | Saprissa | Comunicaciones | 1 : 2, 4 : 3 |
Semi-finals
| 1 | Forge | Motagua | 0 : 0, 2 : 2 |
| 2 | Guastatoya | Comunicaciones | 1 : 2, 0 : 1 |
Final
| 1 | Motagua | Comunicaciones | 2 : 4, 1 : 2 |
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