2021 Main
| Pl | W | D | L | Diff | Pts | |||
| 1 | Peninsula | 26 | 19 | 3 | 4 | 72:25 | 47 | 60 |
| 2 | Brisbane U21 | 26 | 17 | 4 | 5 | 82:31 | 51 | 55 |
| 3 | Olympic FC | 26 | 16 | 7 | 3 | 52:19 | 33 | 55 |
| 4 | Queensland Lions | 26 | 16 | 5 | 5 | 76:34 | 42 | 53 |
| 5 | Sunshine Coast Wanderers | 26 | 16 | 3 | 7 | 58:42 | 16 | 51 |
| 6 | Gold Coast Knights | 26 | 15 | 1 | 10 | 53:40 | 13 | 46 |
| 7 | Moreton Bay Utd | 26 | 14 | 3 | 9 | 75:57 | 18 | 45 |
| 8 | Gold Coast Utd | 26 | 11 | 4 | 11 | 47:39 | 8 | 37 |
| 9 | Eastern Suburbs | 26 | 9 | 5 | 12 | 37:58 | -21 | 32 |
| 10 | Logan Lightning | 26 | 8 | 5 | 13 | 44:54 | -10 | 29 |
| 11 | Capalaba FC | 26 | 7 | 3 | 16 | 33:70 | -37 | 24 |
| 12 | Redlands | 26 | 5 | 3 | 18 | 32:67 | -35 | 18 |
| 13 | Brisbane Strikers | 26 | 2 | 2 | 22 | 21:81 | -60 | 8 |
| 14 | Magpies Crusaders | 26 | 2 | 2 | 22 | 20:85 | -65 | 8 |
Promotion ~ NPL ACT (Final Stage: )
Promotion ~ NPL Queensland (Play Offs: )
Relegation
2021 Play Offs
Semi-finals
| 1 | Peninsula | Queensland Lions | 0 : 1 |
| 2 | Brisbane U21 | Olympic FC | 0 : 3 |
Final
| 1 | Queensland Lions | Olympic FC | 3 : 1 |
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