2021 Apertura
| Pl | W | D | L | Diff | Pts | |||
| 1 | Dock Sud | 18 | 11 | 5 | 2 | 22:10 | 12 | 38 |
| 2 | Central Cordoba | 18 | 9 | 8 | 1 | 14:5 | 9 | 35 |
| 3 | Laferrere | 18 | 7 | 9 | 2 | 29:20 | 9 | 30 |
| 4 | Argentino de Merlo | 18 | 8 | 5 | 5 | 30:23 | 7 | 29 |
| 5 | Atlas | 18 | 6 | 9 | 3 | 23:15 | 8 | 27 |
| 6 | Real Pilar | 18 | 6 | 9 | 3 | 22:15 | 7 | 27 |
| 7 | Excursionistas | 18 | 8 | 3 | 7 | 27:21 | 6 | 27 |
| 8 | Ituzaingo | 18 | 7 | 6 | 5 | 20:19 | 1 | 27 |
| 9 | Club Lujan | 18 | 5 | 10 | 3 | 16:12 | 4 | 25 |
| 10 | Sportivo Italiano | 18 | 5 | 10 | 3 | 26:24 | 2 | 25 |
| 11 | El Porvenir | 18 | 6 | 3 | 9 | 15:20 | -5 | 21 |
| 12 | General Lamadrid | 18 | 5 | 5 | 8 | 9:18 | -9 | 20 |
| 13 | San Martin Burzaco | 18 | 4 | 7 | 7 | 21:26 | -5 | 19 |
| 14 | Midland | 18 | 5 | 4 | 9 | 18:24 | -6 | 19 |
| 15 | Berazategui | 18 | 4 | 6 | 8 | 20:23 | -3 | 18 |
| 16 | Claypole | 18 | 2 | 11 | 5 | 11:17 | -6 | 17 |
| 17 | Victoriano A | 18 | 4 | 5 | 9 | 19:26 | -7 | 17 |
| 18 | Deportivo Espanol | 18 | 4 | 4 | 10 | 11:19 | -8 | 16 |
| 19 | Leandro N. Alem | 18 | 3 | 5 | 10 | 11:27 | -16 | 14 |
Promotion ~ Primera C (Play Offs: Final)
2021 Clausura
| Pl | W | D | L | Diff | Pts | |||
| 1 | Berazategui | 18 | 11 | 4 | 3 | 31:19 | 12 | 37 |
| 2 | Ituzaingo | 18 | 10 | 7 | 1 | 23:12 | 11 | 37 |
| 3 | Deportivo Espanol | 18 | 9 | 6 | 3 | 21:12 | 9 | 33 |
| 4 | Sportivo Italiano | 18 | 7 | 8 | 3 | 21:11 | 10 | 29 |
| 5 | Laferrere | 18 | 8 | 4 | 6 | 21:21 | 0 | 28 |
| 6 | Excursionistas | 18 | 7 | 6 | 5 | 25:23 | 2 | 27 |
| 7 | Claypole | 18 | 7 | 5 | 6 | 19:18 | 1 | 26 |
| 8 | Central Cordoba | 18 | 6 | 8 | 4 | 15:14 | 1 | 26 |
| 9 | Argentino de Merlo | 18 | 6 | 7 | 5 | 32:26 | 6 | 25 |
| 10 | Dock Sud | 18 | 7 | 4 | 7 | 19:21 | -2 | 25 |
| 11 | Real Pilar | 18 | 5 | 8 | 5 | 16:10 | 6 | 23 |
| 12 | General Lamadrid | 18 | 5 | 7 | 6 | 21:23 | -2 | 22 |
| 13 | San Martin Burzaco | 18 | 5 | 6 | 7 | 17:23 | -6 | 21 |
| 14 | Atlas | 18 | 4 | 8 | 6 | 20:26 | -6 | 20 |
| 15 | Club Lujan | 18 | 4 | 7 | 7 | 18:20 | -2 | 19 |
| 16 | Victoriano A | 18 | 4 | 6 | 8 | 26:30 | -4 | 18 |
| 17 | Midland | 18 | 4 | 5 | 9 | 16:22 | -6 | 17 |
| 18 | Leandro N. Alem | 18 | 3 | 7 | 8 | 9:21 | -12 | 16 |
| 19 | El Porvenir | 18 | 1 | 3 | 14 | 10:28 | -18 | 6 |
Promotion ~ Primera C (Play Offs: Final)
2021 Play Offs
Final
| 1 | Berazategui | Dock Sud | 0 : 2, 0 : 0 |
2021 Promotion - Play Offs
Quarter-finals
| 1 | Berazategui | Bye | |
| 2 | Laferrere | Argentino de Merlo | 0 : 1 |
| 3 | Ituzaingo | Excursionistas | 1 : 0 |
| 4 | Central Cordoba | Sportivo Italiano | 0 : 2 |
Semi-finals
| 1 | Berazategui | Argentino de Merlo | 0 : 0, 0 : 1 |
| 2 | Ituzaingo | Sportivo Italiano | 2 : 1, 0 : 0 |
Final
| 1 | Argentino de Merlo | Ituzaingo | 0 : 3, 2 : 0 |
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